Addressing Antibiotic Resistance and Livestock Use

Antibiotics Use Livestock ResistanceFor many Americans purchasing food products at local grocery stores and retailers, there has been a growing movement to learn more about where our food comes from. Many food consumers have been asking to know who produces their food and under what conditions it was raised. Many people are asking for more transparency from food companies in order to learn more about the farming and ranching practices in place. As members of the farming and ranching community, we have a vital role in providing that information.

One of the more frequently discussed topics among food customers today is about the role of antibiotics use in livestock systems. As livestock producers, we understand there are variety of tools used on farms, ranches and feedlots which include vaccines, good nutrition programs and proper housing to keep animals healthy. Antibiotics are only one tool in a plan of good production practices to raise healthy animals. We also understand the importance of judicious use of these tools to keep them effective for animal health, food safety, costs, and proper management.

Last week, PBS Frontline aired an episode focused on the use of antibiotics and questions surrounding the cause of increasing antibiotic resistance in the human population. Though there are several possible sources for this medical trend, livestock were focused on as a possible cause. As members of the livestock we understand the continual to improve the way we utilize tools such as antibiotics, but we may not always communicate that clearly. It is a cooperation between local producers, veterinarians and federal officials who collaborate to improve our methods with food safety in mind.

With that in mind, we have a few points to address on the issue of antibiotic use in food animals and it’s relation to food safety. To learn more about these topics, be sure to consult your local veterinarian and be sure to share examples of how you ensure judicious and responsible antibiotic use on your livestock operation.

Antibiotic Resistance

Antibiotic resistance is incredibly complex and it’s rare for a strain of bacteria from our food supply to be resistant to antibiotics. 

  • Antibiotic resistance occurs when antibiotics attack the majority of bacteria but a few may survive and “mutate” or adapt to the drugs in ways that help them resist treatment by the same drug in the future.
  • The vast majority of antibiotic resistant bacteria are non-foodborne, emerging decades ago in hospital settings or communities and are not linked to animals in our food system.
  • There are occasional cases of antibiotic resistant foodborne bacteria, such as antibiotic resistant salmonella, but those cases are rare.

The chance a person becomes ill from antibiotic resistant foodborne bacteria and not being able to be treated with alternative antibiotics is slim, with many safeguards built in to keep it from happening, such as responsible antibiotic use, research and surveillance.

  • In order for foodborne bacteria to become resistant and impact human health, the bacteria would have to develop a resistant animal strain, survive food processing and handling, proper cooking and find a human with an illness/weakened immune system as the host, survive the human’s body (which will naturally fight the bacteria) and result in a human seeking treatment with the same antibiotic that was used to treat the animal. If antibiotic resistant bacteria were to cause human illness, it means that the standard treatment doesn’t work and that other treatments may have to be considered. So, people becoming ill from antibiotic resistant foodborne bacteria and not being able to be treated in some manner, is extremely rare.  

Farmers, ranchers, veterinarians and animal health experts work together to make sure they’re using antibiotics responsibly, in order to reduce the chances of antibiotic resistance forming. 

In the animal agriculture industry, we work hard to stop the potential formation of antibiotic resistant bacteria by using antibiotics responsibly:

  • Identify the right illness that the animal has by consulting with animal health experts and veterinarians when necessary
  • Pinpoint the right treatment and dose needed to treat that specific illness, condition or concern
  • Administer the antibiotic for the right amount of time by following the law and clear label instructions (not stopping antibiotics early, which is a threat for antibiotic resistance in humans)
  • Conduct the right research to make sure that we continue to protect both animal and human health

Continued research on antibiotic resistance is needed to fully understand antibiotic resistance and address questions about multiple resistance, or co-resistance, which is when bacteria become resistant to several different types or classes of antibiotics and the agriculture community is committed to being part of this important research and dialogue.

  • The agricultural community is proactively working to minimize future risk and continuing to conduct research to look at this important topic.
  • Everyone – farmers, ranchers, veterinarians, doctors, the government, researchers and companies working in animal or human medicine – needs to work collaboratively to protect animal and human health.
  • The agricultural industry is committed to looking at any and all opportunities to mitigate antibiotic resistance in order to make sure we’re continuing to improve the way we use these very important tools.

Antibiotic Use in the Livestock Industry

We can all agree that healthy animals are the basis of a healthy, humane and safe food supply.

  • When antibiotics are used, they are used judiciously to keep the potential risk extremely low of developing antibiotic resistant bacteria that is harmful to people.
  • The beef community has invested in quality assurance programs, research and education designed to maintain high standards of animal care and health and to help us continuously improve how we use antibiotics.
  • Farmers and ranchers have no reason to overuse antibiotics but rather every reason to use them as selectively as possible. For one, it’s the law, but antibiotics also are a costly input for the small business men and women who raise cattle for beef.
  • If farmers did not treat sick animals, many would suffer and die.  This would be inhumane.

The livestock community, including farmers, ranchers, veterinarians, the federal government and the animal health companies that make antibiotics, proactively are working together to continuously improve the way we responsibly use antibiotics in livestock.

  • Changes in FDA Guidance 209 and 213 that will eliminate growth promotion uses of medically important antibiotics and extend veterinary oversight.
  • Within about four years, any medically important antibiotics used in animals will only be for therapeutic purposes and under the supervision of a veterinarian.

To learn more about the use of antibiotics in livestock production, visit with a local veterinarian or find a farmer or rancher in the area to ask their perspectives. You can also find more online tools and information at these links:

National Cattlemens Beef USA logo

An Overview of the FDA Final Guidance 213 and Proposed Veterinary Feed Directive (VFD)

National Cattlemens Beef USA logoBy Dr. Kathy Simmons, DVM, NCBA Chief Veterinarian

On Dec. 12, the Food and Drug Administration (FDA) published their final Guidance #213 and a proposal for revisions to the current Veterinary Feed Directive (VFD). These revisions proposed for the VFD are in response to complaints from stakeholders that the current VFD process can be burdensome. This current guidance is part of FDA’s larger strategy for judicious use of the antibiotics that are most important for use in human medicine and are currently used in feed and water for food-producing animals. Guidance #213 is directed toward the use of these products in feed and water and pertains to the medically important antibiotic classes listed in Appendix A of Guidance 152. The specific drugs or product applications affected by Guidance #213 can be found in a list on the FDA website here.

Guidance #213 does not pertain to the ionophores, such as monensin, unless used in a combination product with a medically important antibiotic.

Guidance #213 is a follow up to final Guidance #209, which states that the antibiotics important to human health should only be used in animal agriculture in ways that are necessary to maintain animal health and with veterinary oversight. Guidance #213 establishes the roadmap for the animal drug manufacturers to phase out the growth promotion use of these products in feed and water over the next three years and revise product labels as needed for use indications of control, prevention and therapy. All medically important antibiotics used in feed and water will require a veterinary prescription or a VFD in order to obtain these products for control, prevention and treatment use.

What is the objective of this FDA guidance? Doubtless, most everyone is aware of the global concern for increasing antibiotic resistance and the problems that antibiotic resistance creates for effectively treating infections in humans and animals. FDA has responsibly chosen to address the concern of antibiotic resistance and its threat to public health. FDA guidance seeks to eliminate the subtherapeutic use of medically important antibiotics in feed and water for growth promotion. The cattle industry, through the Beef Quality Assurance program, also supports this stance by stating in the Judicious Antibiotic Use Guidelines that, “Subtherapeutic Antibiotic Use is Discouraged: Antibiotic use should be limited to prevent or control disease and should not be used if the principle intent is to improve performance.”

So, what does this guidance really mean for cattlemen and women? The loss of the medically important antibiotics for growth promotion has only a minimal impact as there are really very few of these products used for growth promotion in the cattle industry. Our current use of antibiotics in feed is primarily for the prevention and control of conditions/diseases such as liver abscesses, coccidiosis and anaplasmosis. The use of these products will still be available in feed and water for control, treatment and prevention through the oversight of the veterinarian by Rx or VFD. It is extremely important to cattlemen and women to have an efficient and dtreamlined VFD process in order to facilitate the timely and uninterrupted access to these